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HPV Cervical Cancer Vaccine Is it necessary for men to fight?

via:科普中国     time:2019/4/30 10:31:45     readed:740

Among them, HPV16 and HPV18 account for 70% of cervical cancer caused by HPV infection, so these two are also the first targets for the prevention of bivalent vaccines.

Is there a high probability that HPV will release cervical cancer?

The relationship between HPV infection and cervical cancer can be seen in the following figure:

More than 90% of cervical cancers are caused by high-risk HPV infection, and cervical cancer ranks second among female cancer deaths worldwide (the first is breast cancer). But not all high-risk HPV infections can cause cervical cancer. In fact, even if infected by HPV, healthy adults have a good chance to remove HPV from the body with their own immunity. However, HPV infection, especially high-risk infections, cannot be ignored, because the possibility of causing cancer is still present and has become the main cause of cervical cancer. In fact, not only cervical cancer, HPV infection can cause cancer in other parts, such as vulva, vagina, anus, penis and even oropharynx.

Yes, you are not mistaken, and men may also develop cancer due to HPV infection. Although men are much less likely to develop cancer due to HPV infection than women, but why can they prevent themselves and their partners from being at risk?

How does HPV harm the Quartet?

Say it is not a shabu-shabu, HPV spread through intimate skin mucosal contact. The most common mode of transmission is sexual contact, including various combinations of contact between the genitals, anus and the oral mucosa. This is also the case, people who do not have sexual contact with others can not have to vaccinate - they directly evade the route of HPV transmission. There are also some less common ways of HPV transmission, such as iatrogenic transmission and mother-to-child transmission, which cannot be ignored.

However, the occurrence of HPV infection to cancer is not a one-off event, usually going through years to a decade. In the early stage of cancer, if the treatment is found in time, a five-year survival rate of more than 90% can be obtained.

Therefore, if sexual contact is carried out under strict protection, and people who have regular physical examinations can completely prevent cervical cancer by monitoring the infection, they do not have to bear the risk of side effects caused by vaccination, even if the probability is very high. low.

I heard that the HPV vaccine is also a double-edged sword?

Prior to the launch of the HPV vaccine in China, the news that the anti-HPV vaccine Cervarix developed by GlaxoSmithKline caused side effects in Japan caught the attention of all countries.

The vaccination of the HPV vaccine has been in the United States for many years. As one of the government's recommended or even free vaccinations, the adverse reactions are not high enough to require special attention. However, when the Japanese government introduced and vaccinated nationwide, Japanese women reported having adverse reactions to HPV vaccine, and even some women who were seriously affected by adverse reactions took the Japanese government to court. Although the vaccine production company investigated the phenomenon of the incidence of such high regional adverse reactions, it did not reach a conclusion. At the same time, the Japanese government also suspended the active promotion of HPV vaccine.

The first 2-valent HPV vaccine approved by mainland China, and also the "Xi Rui Shi" that caused adverse reactions in Japan.

Although the development and production of vaccines are strictly monitored, they will undergo animal experiments and multi-phase clinical trials before they go on the market. However, due to differences in human body quality, even vaccines that have been promoted for many years cannot guarantee 100%. safety. For diseases that are difficult to control, such as measles and polio, widespread vaccination is undoubtedly the best choice for the entire human population.

However, HPV has its own particularity. First, the transmission route can be controlled. Second, the pathogenicity and mortality rate are not as high as those of measles and polio. Under such circumstances, the effects of adverse reactions caused by vaccines will be amplified. Therefore, for low-risk groups with regular physical examination and asexual contact, the utility of HPV vaccine is not advantageous. For people who are sexually active and unable to perform regular physical examinations, HPV vaccine is undoubtedly an effective barrier against cervical cancer.

So, do you want to fight cervical cancer vaccine?

1. You see this topic from a variety of media chasing hot spots. You didn't know "HPV" and "cervical cancer" before, and it is likely to be forgotten after this topic falls out of the hot search list - it is highly recommended

2, you are very concerned about your health, sexual contact has adequate protective measures, regular physical examination, strict implementation of cervical smear every year or every other year - if you can maintain healthy habits, then no need to inject

3, you are jealous of abstinence or pure desire, life has never had sexual contact with others before, and is not ready to have in the future - no need to inject

Of course, the injection of HPV vaccine does not represent a cervical cancer immunity. The vaccines currently on the market can only cover a subset of HPV types, and there are some rare high-risk types that can escape the regulation of vaccines. In addition, although the vast majority of cervical cancers are caused by HPV infection, a small number of cases still originate from other causes. Therefore, even if you have a vaccine, you should do the same.

HPV infection induces cancer in all parts of the body (Source: wikipedia has changed)

Additional question one

Is it necessary to re-inject the HPV vaccine in five years?

Because the time to market for vaccines is still relatively short, research on the duration of vaccines is limited. The current study classifies samples of no less than five years into "long-term" subgroups, but as to when the vaccine expires, it remains to be verified.

Additional question two

Is the subtype of HPV vaccine prevention in foreign countries the same as China?

Some people who want to go abroad to inject HPV vaccine worry that the subtype of foreign vaccine prevention is different from China, which is completely unnecessary. Because epidemiological studies have shown that HPV16 and HPV18 in China also account for about 70% of HPV infections in cervical cancer, which is almost identical to foreign statistics.

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