On September 18, IT's home According to the Chinese Academy of Sciences, Shanghai institute of microsystem and information technology, Chinese Academy of Sciences Shanghai micro system TaoHu team cooperation with Shanghai jiaotong university xiao-xia, zhi-gang qian, innovation development gene recombinant spider silk protein photoresist, by optimizing the recombinant spider silk genes and molecular weight, combined with a massive simulation based on the number of millions of electronic, Real-time control of acceleration voltage controls the penetration depth, residence position and energy absorption peak of electrons in silk protein photoresist, realizing true 3d nano functional device direct writing with molecular accuracy.
Source: Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences
According to the introduction, the processing accuracy of this technology can reach 14 nm, close to the size of natural silk protein single molecule (~10 nm), one order of magnitude higher than the previous technology. Spider silk protein, excellent mechanical strength for the complex 3 d nanostructures provide critical support, good biocompatibility to allow further through functionalization, implementation can take medicine, can drive, biodegradable 4 d nano functional devices (deformable) of time and space, the intelligent bionic perception, drug delivery nanobots, kind of researches, such as organ chip has definite application prospect.
The study was published in Nature Communications on 26 August 2021, IT House learned.
So far, Tao Hu team has basically completed the establishment of a complete set of 2D and 3D micro-nano processing system for silk protein, including 2D& AMP; 3D electron beam lithography, 2D& AMP; 2.5D ion beam lithography, 2D ULTRAVIOLET lithography, 2D near field lithography, 2D& AMP; 3D soft lithography, 2D& AMP; 3D nano imprint, 2D& AMP; 3D self-assembly and 2D inkjet printing, covering nanometer, micron to millimeter and wafer scale, enables silk proteins to transform from traditional textile materials to medical materials to integrated circuits and sensor materials.