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Omicron from an AIDS patient? One expert came up with a new conclusion: Too surprising

via:快科技     time:2021/12/4 22:01:20     readed:122

As Omicron strain has up to 32 mutations in its spike protein, it has attracted the attention of experts around the world. There are no definitive answers as to how this new variant, the Novel Coronavirus, evolved.

According to foreign media reports, through further research on Omicron, scientists believe that the strain may not have evolved in the human body, but through the evolution of animal hosts.

At the time the Omicron strain was discovered, it was found to have as many as 32 mutations in its spike protein. Single outbreak ” Accumulated in,This suggests it may be a chronic infection in people with weakened immune systems, such as untreated HIV or AIDS patients.

However, after studying unusual mutations in the Omicron strain,The virus may not have evolved in humans, but in an animal host.

Immunologist Christian & Middot, Scripps Research Institute; While most experts believe Omicron came from someone with a compromised immune system, that makes sense, says Kristian Andersen, a professor at The University of California, San Francisco.

However, it could also be a kind of “ Reverse zoonosis & RDquo; Because some of these mutations are very abnormal, or they could come from an animal, and that's a possibility that you can't ignore.

Robert & Middot, professor of microbiology and immunology, Tulane University School of Medicine; Robert Garry has also been studying the unusual mutation in Omicron.It found that seven of these mutations were associated with rodents, allowing it to be better adapted to live in rodents.

The early Novel coronavirus strains are not contagious to animals, but with the emergence of mutations of Alpha, Beta and Delta, some animals are likely to be infected, including rodents, Dr. Gary said.

So if Omicron really came from an animal,It could have infected mice sometime in 2020, and eventually the virus evolved, accumulating about 50 mutations in the spike protein, and then jumped back into humans.


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