Original title: Omir Rong mutant plant BA.4/5 out of control in the United States: 35 days have soared 21 times

According to the latest data released by the US Centers for Disease Control (CDC),As of June 11, local time, the proportion of new infections caused by the new crown virus BA.4 and BA.5 in the United States has reached 21.6 %.

Previously, on June 4th, this ratio was only 13.1 %,May 7th is only 1 %That is, in just 35 days, it has increased by nearly 21 times, and it is expected that it will soon become the main popular strains.

BA.4 and BA.5 are the two seed variants under Omikon Branch B.1.1.529. The mutation sites on the spiny protein are the same. It was first tested in January and February this year. Essence

in Europe,BA.5 has become the most popular mutant strain in Portugal, and the proportion of new infections accounts for about 87 %. At the same time, the number of new deaths returned to the level at the peak of Omikon infection from January to February this year.

European countries such as Austria, Belgium, Denmark, France, Germany, Ireland have also detected BA.4 and BA.5, which also faces great threats.

The infection of BA.4 and BA.5 has not been found at present than BA.1 and BA.2, butIt may be easier to infect the alveoli epithelial cells of the lungs.

Studies have shown that the mutation of new coronal virus variants on the spiny protein L452, such as the L452R carried by BA.4 and BA.5, will increase the number of effective reproduction of the virus.

Cell experiments show that BA.4 and BA.5 is more efficient than BA.2 in human alveoli epithelial cells, and has higher pathogenicity in hamster experiments.