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The United States has approved the first fecal transplant to treat disease by transplanting someone else's feces

via:快科技     time:2022/12/6 12:01:21     readed:186

It has long been known that organs can be transplanted,Do you know about fecal transplants? It can also be used to cure diseases!

A drug called Rebyota has reportedly become the first fecal transplant product approved for use by the US Food and Drug Administration (FDA).

The treatment, developed by Swiss company Hueling Pharmaceuticals, uses stool from a healthy donor to prevent recurrent Clostridium difficile (CDI) infections in adults.


According to the report, between 15,000 and 30,000 people die from CDI each year in the United States. This happens because the gut microbiome is disrupted by antibiotics, leading to the proliferation of a toxin-producing bacterium known as CDI.

Symptoms of the disease include diarrhea, abdominal pain, fever and even organ failure, and up to 25 percent of patients experience repeated infections after their first infection.

Treatment options for the disease are limited, and Rebyota is administered rectum,使用健康捐赠者的粪便恢复已经完成CDI抗生素治疗的患者肠道中的细菌平衡。

Feces for transplantation

According to experts, fecal transplantation is actually the same principle as bone marrow transplantation and liver transplantation, which is to transplant a healthy person's organ into the patient's body, and then make the patient's disease get certain relief.

But the main body of the fecal transplant is not an organ, but an internal environment.

Often patients with intestinal disease have a disordered microbiota, and if a whole healthy microbiota can be implanted, the balance can be restored.

At the same time, the extracted fecal bacteria not only need to be refined by the machine, but also need to go through more than three times of washing. Many impurities in feces have been removed, and its safety can be compared with normal saline.

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